Hell, even "You Deserve a Drink" can sometimes be re-routed into virgin beverages that give great sugar highs (frozen drinks, "girl drinks", mock-tails). My daughter's favorite is the "Lexi Mimosa": seltzer and orange juice.
Cotton ball and petroleum jelly challenge:
The Hot Pepper Challenge (tip: WEAR GLOVES while you attempt this or any "hot pepper" challenge)
The AOTS hot sauce shots "mega dare"